John Burdon Sanderson Haldane was a giant among men. He made major contributions to genetics, population biology, and evolutionary theory. He was at once comfortable in mathematics, chemistry, microbiology and animal physiology. But it was his belief in education that led to his preparing his popular essays for publication. In his own words: "Many scientific workers believe that they should confine their publications to learned journals. I think that the public has a right to know what is going on (...) inside the laboratories, for some of which it pays." So begins Haldane's collection of essays, perhaps the most public intellectual communicating science before the writings of Stephen Jay Gould. The first part of the volume emphasizes the important developments in biology and natural science in the first quarter of the century. As such, it provides a benchmark for studies of the next three quarters of the century. In an unusual introduction, Price takes the readers through their paces, discussing the situation then and now in vitamins, oxygen want, disease controls, and the rewards of science as such. This is followed by Haldane's views on society, art, religion and economy as seen through the eyes of a politically alert major scientist. The editor provides readers unfamiliar with Haldane with a carefully rendered chronology of a life that began in 1892 and that spanned much of the present century. Despite ideas on race, class and politics that have seen better times, Haldane was truly exceptional in translating the science of his time into ideas that "everyman" could readily grasp. His predictions on what science would achieve were on target far more often than not. But even his failed predictions are perhaps the most interesting of all. They throw into sharp relief the truly novel and revolutionary developments in science over the past 75 years. J.B.S. Haldane held many positions and received many honors during his lifetime. But for most of the period covered in this volume, he was the William Dunn Reader in Biochemistry at Cambridge University. He simultaneously served as Fellow of New College, in Oxford University's Horticultural Institute. Carl A. Price served until 1999 as professor IIof plant molecular biology in the Waksman Institute of Microbiology at Rutgers, the State University of New Jersey. He also served as the editor of Plant Molecular Biology Reporter from 1983 until 1997. This is the first volume in a new series on the history and theory of science. (shrink)

Background: The factors influencing parents’ willingness to enroll their children in biobanks are poorly understood. This study sought to assess parents’ willingness to enroll their children, and their perceived benefits, concerns, and information needs under different consent and data-sharing scenarios, and to identify factors associated with willingness. Methods: This large, experimental survey of patients at the 11 eMERGE Network sites used a disproportionate stratified sampling scheme to enrich the sample with historically underrepresented groups. Participants were randomized to receive one of (...) three consent and data-sharing scenarios. Results: In total, 90,000 surveys were mailed and 13,000 individuals responded (15.8% response rate). 5737 respondents were parents of minor children. Overall, 55% (95% confidence interval 50–59%) of parents were willing to enroll their youngest minor child in a hypothetical biobank; willingness did not differ between consent and data-sharing scenarios. Lower educational attainment, higher religiosity, lower trust, worries about privacy, and attitudes about benefits, concerns, and information needs were independently associated with less willingness to allow their child to participate. Of parents who were willing to participate themselves, 25% were not willing to allow their child to participate. Being willing to participate but not willing to allow one’s child to participate was independently associated with multiple factors, including race, lower educational attainment, lower annual household income, public health care insurance, and higher religiosity. Conclusions: Fifty-five percent of parents were willing to allow their youngest minor child to participate in a hypothetical biobank. Building trust, protecting privacy, and addressing attitudes may increase enrollment and diversity in pediatric biobanks. (shrink)

A splendid edition. Schneewind's illuminating introduction succinctly situates the _Enquiry_ in its historical context, clarifying its relationship to Calvinism, to Newtonian science, and to earlier moral philosophers, and providing a persuasive account of Hume's ethical naturalism. --Martha C. Nussbaum, Brown University.

Early in this century, only a few biologists accepted that natural selection was the chief cause of evolution, until the independent calculations of John Burdon Sanderson Haldane (1892–1964), Sewall Wright and R. A. Fisher demonstrated that ideal populations subject to Mendel's laws could behave as Darwin had said they would. Evolutionary theorist John Maynard Smith, a student of Haldane's, has raised the question of why Haldane, who was no naturalist, took up the subject of evolution, and he suggests that (...) the answer may have to do with Haldane's lively interest in religion. In fact Maynard Smith's answer has much more evidence in its favour than he knew. (shrink)

This book, first published in 1938, is based on the Muirhead Lectures given at Birmingham University in February and March of 1937. The first half of this book is mainly devoted to an exposition of the principles of genetics, whilst the second half deals with more controversial topics, with the text providing an insight into the ideology of the time. This title will be of interest to students of politics and history.

The contention that the Homeric epics, and perhaps also the Hesiodic poems and the Homeric Hymns, are the products, directly or at a very short remove, of a tradition of orally improvised poetry is widely accepted as a basic premiss in Homeric criticism. The cogency of the argument depends on the frequency and characteristic use of formulae in the early hexameter poetry, and their rarity in the literature of Classical, Hellenistic, and Roman times, which is known or assumed to have (...) been composed in the study. The reasoning appears to me valid, but in some respects overstated or ambiguously stated in recent publications, and the first fault arises out of the second. (shrink)

Il y a un conflit entre les normes surnaturelles qui ne tiennent pas compte des possibilités humaines et les normes naturelles qui conduisent à des règles d’action fondées sur la connaissance positive du milieu où nous vivons ; mais il est impossible que les secondes affranchissent l’homme des premières. La question de leur accord se trouve donc posée.

Prior thinks that Edwards' argument depends on a metaphysical turn of phrase. Edwards, he says, subsumes "all happenings, or anyhow... all changes, under the idea of the 'beginning to be' either of concrete objects or of abstract ones". We are not to say, "My head began to ache," we are to say, "My headache began to exist." The shift may seem trivial, but actually it is "of the very first importance": Edwards' argument "depends on it." The reason is the following. (...) Edwards says that objects or substances cannot begin to be without a cause; that if they could, it would be prima facie implausible to hold that substances of only one kind, of all the millions of kinds of substance, should causelessly come to be; and that the implausibility cannot be removed by appealing to the nature of what thus comes to be, because until it actually exists there is nothing there to explain anything. Prior agrees with all that. But he holds that it is not impossible that some already existing substances should have a special kind of property which would make it possible for them to change or act causelessly. Of course, if we have to say that a change or an act is just another kind of coming to be of a substance, this too is impossible. Hence Prior thinks that by showing that changes and acts need not be construed as Edwards construes them, he will have made room for the possibility of limited indeterminism. (shrink)

The ‘modern’ natural law philosophers of the seventeenth century believed that conflict was an unavoidable concomitant of human intercourse, rooted in our nature. They understood the normative laws of nature as serving the purpose of setting the limits within which conflict is compatible with lasting social cooperation, thus showing, in effect, how warfare can be turned into competition. The natural lawyers were interested primarily in legal and political problems, not in ethics. But in order to provide reasoned approaches to immediate (...) practical issues, they had to move to a level of abstract theorizing at which philosophical claims about morality were unavoidable. Natural law theory with its understanding of the central underlying problem of human sociability dominated seventeenth-century practical philosophy, and the solutions its various proponents offered generated many of the central concerns of what we know as moral philosophy. (shrink)

The first volumes of the great University of Toronto Press edition of the works of John Stuart Mill, edited by John M. Robson, appeared in 1963, and the edition was completed in 1991. Not surprisingly, it has generated a great deal of discussion of Mill's thought. The bibliography in John Skorupski's Companion to Mill lists some 350 items pertinent to Mill published since 1963, although it makes no attempt at comprehensive coverage of English-language studies and has nothing in any foreign (...) language. No one can keep up with all of this secondary material. It is not the least of the virtues of the Companion that it gives us a broad survey of much of the recent research and thought about Mill. I suspect that some of the articles will not be very helpful to bewildered undergraduates hoping for a boost on an assignment. But all of them will be useful to advanced students and scholars who want to know where we are on Mill these days. (shrink)